mpm cell line nci h2452  (ATCC)

Journal: Pathology Oncology Research

Article Title: The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma

doi: 10.1007/s12253-019-00652-x

Figure Lengend Snippet: Immunoblotting analysis of the COX-2, 5-LOX and 12-LOX proteins. The relative expression, following normalisation of the bands shown in Fig. 3 (a), is summarised for 3 MPM cell lines (NCI-H2452, NCI-H2052, MSTO-211H) and the NSCLC cell line A549

Article Snippet: The MPM cell lines NCI-H2452, NCI-H2052 and MSTO-211H were obtained from the American Type Culture Collection (ATCC).

Techniques: Western Blot, Expressing

Journal: Pathology Oncology Research

Article Title: The Investigation of Lipoxygenases as Therapeutic Targets in Malignant Pleural Mesothelioma

doi: 10.1007/s12253-019-00652-x

Figure Lengend Snippet: The effect of arachidonic acid pathway inhibitors on MPM cells. As shown in Table 2 , all cell lines demonstrated expression of 5-LOX, 12-LOX and COX-2 proteins. The IC50 values, calculated from the data shown in Fig. 3 , are shown for the MPM cell lines (NCI-H2452, NCI-H2052, MSTO-211H) and the NSCLC cell line A549. For reference, the published human Cmax range for each inhibitor was converted into the equivalent molar concentrations. Baicalein, MK-886 and licofelone do not currently have a published recommended daily dose and therefore the clinically achievable Cmax may be higher than shown

Article Snippet: The MPM cell lines NCI-H2452, NCI-H2052 and MSTO-211H were obtained from the American Type Culture Collection (ATCC).

Techniques: Expressing